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No. de sistema: 000006762

LDR _ _ 00000nab^^22^^^^^za^4500
008 _ _ 171031m20179999xx^^r^p^^^^^^z0^^^a0eng^d
040 _ _ a| ECO
c| ECO
044 _ _ a| xx
245 0 0 a| Degradation of sodium metamizole by enzymatic extracts from some white rot fungi
520 1 _ a| White rot fungi are known for their highly efficient ability to degrade environmental pollutants, such as pharmaceuticals. We investigated the ability of enzymatic extracts from Auricularia fuscosuccinea, Lentinula edodes, Ganoderma lucidum, Agrocybe aegerita, Pleurotus ostreatus, P. djamor and P. eryngii to degrade the analgesic drug metamizole. The formation of 4-MAA and 4-AA metabolites was also monitored. Total degradation of 50 mg l-1 of the drug was achieved with the extract obtained from A. fuscosuccinea ECS-210 within three days. Under the best conditions (pH 5.6, 35 °C and 110 rpm), the degradation profile followed the behavior of pseudo-first order kinetics with a coefficient k = 0.0779 L mg-1h-1. The enzymatic activity tests showed evidence for the presence of laccases, lignin peroxidases and phenoloxidases.
650 _ 4 a| Hongos
650 _ 4 a| Metamizole de sodio
650 _ 4 a| Medicamentos
650 _ 4 a| Enzimas ligninolíticas
650 _ 4 a| Biorremediación
700 1 _ a| Mayorga Santis, Rosario
700 1 _ a| Sánchez, José E.
e| coaut.
n| 55452597200
700 1 _ a| Gutiérrez Hernández, Rubén Fernando
e| coaut.
700 1 _ a| Calixto Romo, María de los Ángeles
e| coaut.
773 0 _
t| Sydowia
g| Vol. 69 (2017), p. 205–214
x| 0082-0598
856 4 1 u| http://www.verlag-berger.at/fileadmin/media_data/ebooks/22-Sydowia-69_Sanchez.pdf
z| Artículo electrónico
901 _ _ a| Artículo con arbitraje
902 _ _ a| GOG / MM
904 _ _ a| Octubre 2017
905 _ _ a| Artecosur
905 _ _ a| Biblioelectrónica
906 _ _ a| Producción Académica ECOSUR
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Degradation of sodium metamizole by enzymatic extracts from some white rot fungi
Mayorga Santis, Rosario (autor)
Sánchez, José E. (autor)
Gutiérrez Hernández, Rubén Fernando (autor)
Calixto Romo, María de los Ángeles (autor)
Contenido en: Sydowia. Vol. 69 (2017), p. 205–214. ISSN: 0082-0598
No. de sistema: 6762
Tipo: - Artículo con arbitraje
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"White rot fungi are known for their highly efficient ability to degrade environmental pollutants, such as pharmaceuticals. We investigated the ability of enzymatic extracts from Auricularia fuscosuccinea, Lentinula edodes, Ganoderma lucidum, Agrocybe aegerita, Pleurotus ostreatus, P. djamor and P. eryngii to degrade the analgesic drug metamizole. The formation of 4-MAA and 4-AA metabolites was also monitored. Total degradation of 50 mg l-1 of the drug was achieved with the extract obtained from A. fuscosuccinea ECS-210 within three days. Under the best conditions (pH 5.6, 35 °C and 110 rpm), the degradation profile followed the behavior of pseudo-first order kinetics with a coefficient k = 0.0779 L mg-1h-1. The enzymatic activity tests showed evidence for the presence of laccases, lignin peroxidases and phenoloxidases."