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No. de sistema: 000037910

LDR _ _ 00000nab^^22^^^^^za^4500
008 _ _ 110414m20109999xx^^r^p^^^^^^z0^^^a0eng^d
040 _ _ a| ECO
c| ECO
044 _ _ a| xx
245 0 0 a| Wild rodents (Dipodomys merriami) used as biomonitors in contaminated mining sites
520 1 _ a| Mining is one of the most important industrial activities globally; however, mining processes have critical environmental impacts, as mining is a major source of metals and metalloids that contribute significantly to the pollution of soil, sediment, water and air. Heavy metals can impact the health of exposed human populations and nonhuman receptors. This study focused on arsenic because its genotoxicity is well-known. Previously, we proposed a methodology to evaluate and integrate risk from a single source affecting different biologic receptors. Here, we propose an alternative approach estimating arsenic exposure in children and kangaroo rats using probabilistic simulation with Monte Carlo modeling. The estimates are then associated to measured DNA damage and compared to both populations of children and rodents living in contaminated and in reference areas. Finally, based on the integrated analysis of the generated information, we evaluate the potential use of wild rodents (Dipodomys merriami) as a biomonitor at mining sites. Results indicate that the variation of genotoxicity in children of the reference site is approximately 2 units when compared to the children of the contaminated site. In the rodents we observed a variation of approximately 4 units between those of the reference site when compared to those living on the contaminated site. We propose that D. merriami can be used as a biomonitor organism in sites with mining activity, and that a non-lethal test can be used to evaluate risk from metal exposure.
700 1 _ a| Espinosa Reyes, Guillermo
700 1 _ a| Torres Dosal, Arturo
e| coaut.
700 1 _ a| Ilizaliturri Hernández, César Arturo
e| coaut.
700 1 _ a| González Mille, Donaji Josefina
e| coaut.
700 1 _ a| Díaz Barriga Martínez, Fernando
e| coaut.
n| 7003742572
700 1 _ a| Mejía Saavedra, Jesús
e| coaut.
773 0 _
t| Environmental Engineering
g| Vol. 45, no. 1 (Jan 2010), p. 82-89
x| 10934529
902 _ _ a| GOG
904 _ _ a| Abrel 2011
905 _ _ a| Artecosur
905 _ _ a| Biblioelectrónica
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Wild rodents (Dipodomys merriami) used as biomonitors in contaminated mining sites
Espinosa Reyes, Guillermo (autor)
Torres Dosal, Arturo (autor)
Ilizaliturri Hernández, César Arturo (autor)
González Mille, Donaji Josefina (autor)
Díaz Barriga Martínez, Fernando (autor)
Mejía Saavedra, Jesús (autor)
Contenido en: Environmental Engineering. Vol. 45, no. 1 (Jan 2010), p. 82-89. ISSN: 10934529
No. de sistema: 37910
Tipo: Artículo
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"Mining is one of the most important industrial activities globally; however, mining processes have critical environmental impacts, as mining is a major source of metals and metalloids that contribute significantly to the pollution of soil, sediment, water and air. Heavy metals can impact the health of exposed human populations and nonhuman receptors. This study focused on arsenic because its genotoxicity is well-known. Previously, we proposed a methodology to evaluate and integrate risk from a single source affecting different biologic receptors. Here, we propose an alternative approach estimating arsenic exposure in children and kangaroo rats using probabilistic simulation with Monte Carlo modeling. The estimates are then associated to measured DNA damage and compared to both populations of children and rodents living in contaminated and in reference areas. Finally, based on the integrated analysis of the generated information, we evaluate the potential use of wild rodents (Dipodomys merriami) as a biomonitor at mining sites. Results indicate that the variation of genotoxicity in children of the reference site is approximately 2 units when compared to the children of the contaminated site. In the rodents we observed a variation of approximately 4 units between those of the reference site when compared to those living on the contaminated site. We propose that D. merriami can be used as a biomonitor organism in sites with mining activity, and that a non-lethal test can be used to evaluate risk from metal exposure."