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7 resultados encontrados para: AUTOR: Romero Sandoval, Natalia Cristina
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Resumen en: Inglés |
Resumen en inglés

A new method using a magnetic nanoparticle-based colorimetric biosensing assay (NCBA) was compared with sputum smear microscopy (SSM) for the detection of pulmonary tuberculosis (PTB) in sputum samples. Studies were made to compare the NCBA against SSM using sputum samples collected from PTB patients prior to receiving treatment. Experiments were also conducted to determine the appropriate concentration of glycan-functionalized magnetic nanoparticles (GMNP) used in the NCBA and to evaluate the optimal digestion/decontamination solution to increase the extraction, concentration and detection of acid-fast bacilli (AFB). The optimized NCBA consisted of a 1:1 mixture of 0.4% NaOH and 4% N-acetyl-L-cysteine (NALC) to homogenize the sputum sample. Additionally, 10 mg/mL of GMNP was added to isolate and concentrate the AFB. All TB positive sputum samples were identified with an increased AFB count of 47% compared to SSM, demonstrating GMNP’s ability to extract and concentrate AFB. Results showed that NCBA increased AFB count compared to SSM, improving the grade from “1+” (in SSM) to “2+”. Extending the finding to paucibacillary cases, there is the likelihood of a “scant” grade to become “1+”. The assay uses a simple magnet and only costs $0.10/test. NCBA has great potential application in TB control programs.


2.
Artículo
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Resumen en: Inglés |
Resumen en inglés

Background Rural communities in the Amazonian southern border of Ecuador have benefited from governmental social programmes over the past 9 years, which have addressed, among other things, diseases associated with poverty, such as soil transmitted helminth infections. The aim of this study was to explore the prevalence of geohelminth infection and several factors associated with it in these communities. Methods This was a cross sectional study in two indigenous communities of the Amazonian southern border of Ecuador. The data were analysed at both the household and individual levels. Results At the individual level, the prevalence of geohelminth infection reached 46.9% (95% CI 39.5% to 54.2%), with no differences in terms of gender, age, temporary migration movements or previous chemoprophylaxis. In 72.9% of households, one or more members were infected. Receiving subsidies and overcrowding were associated with the presence of helminths. Conclusions The prevalence of geohelminth infection was high. Our study suggests that it is necessary to conduct studies focusing on communities, and not simply on captive groups, such as schoolchildren, with the object of proposing more suitable and effective strategies to control this problem.


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Artículo
Acercamiento al perfil de las mujeres violentadas en la región centro-andina del Ecuador
Ávila Paredes, Janneth P. ; Rodríguez Sánchez, Dolores A. (coaut.) ; Cevallos, Ana Cristina (coaut.) ; Monserrat Jerves, Elena (coaut.) ; Romero Sandoval, Natalia Cristina (coaut.) ; Sánchez Pérez, Héctor Javier (coaut.) (1960-) ;
Contenido en: Ágora. Estudos Clássicos em Debate Vol. 2, no. 2 (Julio - Diciembre 2015), p. 214-219 ISSN: 2412-804X
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Resumen en: Español | Inglés |
Resumen en español

Objective: Identify the profile of women victims of violence that starts the path of care in specialized centers in the ecuadorian andean region center and characterize the environment of the violence.Materials and Methods: We reviewed 1091 records of cases treated during the year 2012 of two organizations specializing in violence toward women in the region andean-central Ecuador. They described the categorical variables (violence verbal, physical, sexual and severe physical) with proportions; the average age and its 95% was used to describe in the categorical variables: age groups, education, marital status, place of violence and type of violence.Results: The 100% of the victims were women in the productive age and the aggressor in the 98.7 % of cases were men. In the records are found from one to nine acts of violence narrated by women. Acts of violence recorded were more frequent, among others: insult 16.7 %, coup with hand or fist 12.0 %; threatens to kill or kill 6.3 %. In seven out of every ten women violence occurred in the home. Conclusion: Women of reproductive age are those that come mostly at the centers of attention, at the request of legal, social and psychological attention spontaneous. The various forms of violence and the environment where mostly occurs must motivate the adequacy of the policies for the prevention, care and protection to women.

Resumen en inglés

Objetivo: Identificar el perfil de la mujer víctima de violencia que inicia la ruta de atención en centros especializados en la región centro andina ecuatoriana y caracterizar el entorno de la violencia. Materiales y Métodos: Se revisaron 1091 registros de casos atendidos durante el año 2012 de dos organizaciones especializadas en violencia hacia la mujer en la región centro andina ecuatoriana. Se describieron las variables categóricas (violencia verbal, física, física severa y sexual) con proporciones; la media de edad y su IC 95%, se usó para describir en las variables categóricas: grupos de edad, instrucción, estado civil, lugar de la violencia y tipo de violencia.Resultados: El 100% de las víctimas fueron mujeres en edad productiva y el agresor en el 98,7% de casos fueron hombres. En los registros se encontraron desde uno hasta nueve actos de violencia narrados por las mujeres. Los actos de violencia más frecuentes registrados fueron, entre otros: insulto 16,7%, golpe con mano o puño 12,0%; amenaza con matar o matarse 6,3%. En siete de cada diez mujeres la violencia ocurrió en el hogar.Conclusion: Las mujeres en edad reproductiva son las que acuden mayoritariamente a los centros de atención, por demanda de atención legal, social y psicológica espontánea. Las diversas formas de violencia y el entorno donde mayoritariamente se produce deben motivar la adecuación de las políticas de prevención, atención y protección a la mujer.


4.
- Artículo con arbitraje
Conformance contrast testing between rates of pulmonary tuberculosis in Ecuadorian border areas
Ortiz Rico, Claudia ; Aldaz, Cristina (coaut.) ; Sánchez Pérez, Héctor Javier (coaut.) (1960-) ; Martín Mateo, Miguel Luis (coaut.) ; Romero Sandoval, Natalia Cristina (coaut.) ;
Contenido en: Salud Pública de México Vol. 57, no. 6 (noviembre-diciembre 2015), p. 496-503 ISSN: 0036-3634
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Resumen en: Español | Inglés |
Resumen en español

Objetivo. Determinar las tasas de sintomáticos respiratorios y de incidencia de tuberculosis pulmonar en dos zonas fronterizas de Ecuador, y contrastarlas con cifras oficiales. Material y métodos. Encuesta transversal aplicada en comunidades fronterizas Sur Oriental (FSO) y Sur Andina (FSA) a 1 598 y 2 419 mayores de 15 años, respectivamente. A los sintomáticos respiratorios se les realizó una baciloscopía en esputo. Las tasas y razón de momios se compararon frente a cifras oficiales mediante contraste de verosimilitudes. Resultados. Las tasas de sintomáticos respiratorios (7.7 y 5.9% en FSO y FSA, respectivamente) y de tuberculosis pulmonar (incidencia acumulada 125 y 140 por 100 000 habitantes, respectivamente) discrepan de las cifras oficiales (0.98 y 0.99% de sintomáticos respiratorios, respectivamente; y, 38.23 por 105 habitantes para tuberculosis pulmonar en Ecuador) (p<0.001). Conclusión. Fortalecer la búsqueda de sintomáticos respiratorios y la vigilancia epidemiológica de la tuberculosis pulmonar en áreas fronterizas.

Resumen en inglés

Objective. To estimate rates of cases of respiratory symptomatic subjects and the incidence rate of pulmonary tuberculosis in two border areas of Ecuador, and contrast them with official figures. Materials and methods. Cross-sectional survey in the southeastern (SEBA), and the Andean southern Ecuadorian border areas (ASBA), which were conducted, respectively, in 1 598 and 2 419 persons aged over 15 years recruited over periods of three weeks. In identified respiratory symptomatic cases, a sputum sample was taken for smear testing. The results (odds ratios and their respective 95% confidence intervals), were compared with local and national official figures using maximum likelihood contrasts. Results. The rates of respiratory symptomatic subjects (7.7% and 5.9% in the SEBA, and ASBA, respectively) and of pulmonary tuberculosis (cumulative incidence rates of 125 and 140 per 100 000 inhabitants, in the same order) were significantly greater than the official figures (of 0.98 and 0.99% for respiratory symptomatic subjects in the SEBA and ASBA, respectively; and of 38.23 per 100 000 inhabitants for pulmonary tuberculosis in Ecuador as a whole) (p<0.001). Conclusion. It is necessary to reinforce both active case finding for respiratory symptomatic subject cases, and epidemiological surveillance of pulmonary tuberculosis in Ecuadorian border regions.


5.
Capítulo de libro - Capítulo con arbitraje
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Tuberculosis (TB) and human rights in Chiapas, Mexico
Sánchez Pérez, Héctor Javier (1960-) ; Gómez Velasco, Anaximandro (coaut.) ; Leal, G. (coaut.) ; Bencomo Alerm, Alied (coaut.) ; Romero Sandoval, Natalia Cristina (coaut.) ; Martín Mateo, Miguel Luis (coaut.) ;
Contenido en: Tuberculosis: expanding knowledge Rijeka, Croatia: InTech, 2015 p. 1-42 ISBN:9789535121398
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6.
- Capítulo de libro con arbitraje
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Pulmonary tuberculosis in Latin America: patchwork studies reveal inequalities in its control – the cases of Chiapas (Mexico), Chine (Ecuador) and Lima (Peru)
Sánchez Pérez, Héctor Javier (1960-) ; Horna Campos, Olivia Janett (coaut.) ; Romero Sandoval, Natalia Cristina (coaut.) ; Consiglio, Ezequiel (coaut.) ; Martín Mateo, Miguel Luis (coaut.) ;
Contenido en: Tuberculosis - current issues in diagnosis and management Rijeka, Croatia: InTech, 2013 p. 465-489 ISBN:978-953-5110-49-1
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7.
Artículo
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Resumen en: Inglés |
Resumen en inglés

SETTING: An aboriginal community of 653 persons. OBJECTIVE: To determine the prevalence of pulmonary tuberculosis (PTB) and to analyse related factors. DESIGN: The total population was surveyed; those with chronic productive cough were asked to provide sputum specimens. PTB was diagnosed by bacilloscopy (acidfast bacilli [AFB]). An analysis of socio-economic factors and clinical history associated with chronic cough or positive smear for PTB was carried out using multiple correspondence analysis and logistic regression models. RESULTS: Two hundred and two patients were identi- fied with chronic cough and 173 with chronic productive cough. Chronic cough was associated with having a history of PTB (adjusted OR 4.89, 95%CI 2.6–9.4) and with work-related migratory movements (adjusted OR 2.05, 95%CI 1.3–3.3). Of 92 coughers with sputum samples analysed, 44 (47.8%) were PTB-positive, giving a prevalence of 6.7% in the whole population. In the groups aged 15–34 and 45 years, women had higher positivity rates than men, whereas in the group aged 35–44 years rates were higher in men. Twenty-seven per cent of families had one to four smear-positive members. CONCLUSION: The Tuberculosis Control Programme in the area studied needs to be strengthened, taking into account the ethnic context, work-related migration and the socio-economic and geographic context.